Acetylate to kill or save

Acetylate to kill or save

Text by Nicole LeBrasseur [email protected] Acetylate to kill or save M ammalian p53 can kill, or it can save. The end result, according to Knights et al. (page 533), depends on opposing acetylation events that send p53 down disparate paths. The stabilization of p53 following cellular damage can trigger either apoptosis or a reversible cell cycle checkpoint that probably gives cells time ...

Are Guns There to Kill or to Save Life?

Gunshots are one of the most common modes of deaths and injuries among young Americans in the post-World War II era [1]. The most effective way to prevent firearm injuries is to remove guns from the home and community [1,2]. High rates of injury and death from firearms in United States (US) are in stark contrast to the cities with no or few cases. This difference is most likely related to firea...

To Save Or Not To Save: The Fisher Game

We examine the Fisher market model when buyers, as well as sellers, have an intrinsic value for money. We show that when the buyers have oligopsonistic power they are highly incentivized to act strategically with their monetary reports, as their potential gains are unbounded. This is in contrast to the bounded gains that have been shown when agents strategically report utilities [5]. Our main f...

DNA vaccines and apoptosis: to kill or not to kill?

The Journal of Clinical Investigation | July 2003 | Volume 112 | Number 1 RNase. Proc. Natl. Acad. Sci. U. S. A. 100:4102-4107. 14. Shinkura, R., et al. 2003. The influence of transcriptional orientation on endogenous switch region function. Nat. Immunol. 4:435–441. 15. Yu, K., Chedin, F., Hsieh, C.L., Wilson, T.E., and Lieber, M.R. 2003. R-loops at immunoglobulin class switch regions in the ch...

Do genes allow inflammation to kill or not to kill?